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How Long Does Lion’s Mane Tincture Last Once Opened?

Updated: Dec 26, 2025

This page explains how long an opened bottle of Lion’s Mane tincture typically lasts, why alcohol-based extracts maintain stability, and what factors influence shelf life during storage.


Lion’s Mane mushroom tincture bottle


Shelf Life After Opening

Alcohol-based tinctures generally maintain stability for extended periods when stored properly. Many bottles remain usable for several years after opening.


What Affects Longevity?

Longevity may depend on alcohol concentration, exposure to heat or light, and how the bottle is stored once opened.


Does Refrigeration Help?

Refrigeration is not typically required. Alcohol preserves tinctures, so room temperature storage away from heat and sunlight is common.


Signs of Degradation

Changes in sediment, aroma, or appearance may indicate a tincture should be replaced.


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